De humani corporis fabrica

This book was revolutionary, illustrating with incredible detail the anatomy of the human body. For the first time, accurate depictions of anatomical structures were integrated with descriptive text for the benefit of medical students and practitioners. These depictions were highly informative, as opposed to mere aesthetic visuals of previous writings. The illustrations were also drawn with a degree of naturalism that was previously unknown, perhaps in congruence with or influencing the way ideas about art were shifting from Byzantine to the more realistic pieces typical of perspectival art.

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