La segregazione degli ebrei – the world’s first Jewish ghetto – was established on March 29, 1516. Before the establishment of the ghetto, Jews in Venice had only been allowed to live on the mainland, not the Dominant (main city of Venice). It was in 1516, after a war between Venice and French and imperial sources, that the Jews fled the mainland and sought refuge in Venice. However, they still feared persecution in Venice and asked that they be “isolated” for their own protection. Ultimately, the establishment of the ghetto segregated the Jewish community from the rest of Venice but also allowed the Jewish culture to flourish. This image is sourced from the Jewish Museum of Venice.