"She had left all that behind her in that little room in Bulstrode Street, where sat the one man in the world that she cared for—the one man, now, who cared for her. There was no one else; there never could be anyone else." (ch 24)

This is a significant location because this is where she and Vincent confessed their love. This place is where Vincent tried to tell Mary he would leave his wife for her and they could run away together.