The Ohio River is a major waterway in the United States ranging from western Pennsylvania and joining the Mississippi River in southern Illinois. The name "Ohio" is from the Seneca word meaning Good River. Major cities on the river include Pittsburgh, PA, Cincinnati, OH, and Louisville, KY.

Louisiana is a state in the southeastern United States of America and is bordered by Texas, Arkansas, and Mississippi. Its capital is Baton Rouge, and its largest city is New Orleans. The area was inhabited by the Caddo, Tunica, Natchez, Houma, Choctaw, Atakapa, and Chitimacha tribes.